alse Peyote. These people make long pilgrimages to the
sacred places where peyote grows in search of that sacrement. They believe that
if a person is has not been properly purified the spirits will lead him to the False
Peyote and if he partakes of it, he will suffer madness or at least a bad trip. The
plant is known among some tribes as Chautle or Chaute. These names are also
used for other Ariocarpus species. This cactus contains hordenine, Nmethyltryamine
in fairly small amounts (about 0.02 percent) and traces of Nmethyl-
3,4-dimethoxy-B-phenethylamine, and N-methyl-4-B-phenethylamine.
Aside from these alkaloids it also contains a flavone called retusin (3,3',4',7-
tetramethoxy-5-hydroxyflavone). Although alkaloid content may very some at
different seasons or stages of growth, from the scientific point of view the
amounts present in this plant appear insufficient to produce any
SUNAMI: This plant, ARIOCARPUS FISSURATUS, has been used in folkoric
medicine of Mexico and southwestern USA. It is believed to be more potent than
peyote and is used in the same manner as that cactus or made into an
intoxicating drink. Among some tribes it is known as Chaute (a generic term for
Ariocarpus species), living rock, or dry whiskey. The latter name, however, is
often used for peyote and other psychoactive cacti. There are two varieties of A.
fissuratus: var. lloydii and var. fissuratus. Both have about the same
phytochemical makeup. The plant contains mostly hordenine, less N-methyltyramine
and some N-methyl-3,4-dimethoxy-B-phenethylamine. Two other
species, A. kotschoubeyanus also known as Pata De Venado or Pezuna De
Venado, and A. trigonus also contain these alkaloids.
DOÑANA: This small cactus, CORYPHANTHA MACROMERIS, from northern
Mexico has been found to contain macromerine, a phenethylamine drug reputed
to have about 1/5 the potency of mescaline. It also contains normacromerine, Nformylnor-
macromerin, tyramine, N-methyltramine, hordenine, N-methyl-3,4-
dimethoxy-B-phenethylamine, metanephrine, and synephrine (a macromerine
precursor). Other coryphantha species which contain macromerine with most of
these other alkaloids include: C. pectinada, C. elephantideus, C. runyonii and C.
cornifera var. echinus. Most of these alkaloids with the exception of macromerine
have also been found in other varieties of C. conifera and in C. durangensis, C.
ottonis, C. poselgeriana and C. ramillosa. Considering that there is usually no
more than 0.1 percent macromerine in Doñana and that a gram or more of this
alkaloid may be needed to produce a psychotropic effect, one would have to
consume more than a kilo of the dried cactus or 20 pounds of the fresh plant.
Clearly this is not possible for most humans. If one wishes to experiment with the
hallucinogenic properties of Doñana, is is necessary first to make an extraction of
the mixed alkaloids. Methods for this are given latter in this guide.
the top of the drum are two threaded openings. Opening number one is
secured with the original bung. The other opening is tightly stuffed with
a rubber stopper. This rubber stopper has a hole drilled in it, and a
section of pipe is put through the hole in the stopper so that it
Extraction And Isolation Of
The Lysergic Acid Amides
extends about an inch below the stopper. To this pipe, a line of
vacuum tubing is attached, leading to a vacuum pump. This pump
should be the typical shop pump that can pull a vacuum of about 21
inches of mercury out of the possible 30 inches. This is enough to
greatly speed the evaporation without causing the chloroform to boil.
Boiling may raise a head of foam that would carry product along with it,
causing great losses.
On a laboratory scale, a stronger vacuum can be used from an
aspirator. By using red or yellow darkroom light bulbs for
illumination, damage to the product can be kept to a minimum. The
stronger vacuum speeds up the process quite a bit. Use boiling chips to
As the chloroform evaporates away, more of the extraction solvent
may be added to either the 55-gallon drum or the distilling flask,
depending upon the scale of production. The evaporation is continued
until the extraction solvent has been reduced to one-fifteenth its
original volume. For the 200-pound crop, the 150 gallons of extraction
solvent has been reduced to 10 gallons.
An accessory which may speed up and smooth out this
evaporation is a capillary air bubbler. This is made by taking a section of
glass tubing, and poking it through a rubber stopper. The end of the
glass tubing is then heated to redness in a flame, and pulled into a
very fine capillary. The tubing is then stuck into the solution being
evaporated, extending nearly to the bottom. The vacuum will pull a
fine stream of air bubbles through the solution and aid evaporation.
When the chloroform has been reduced to one-fifteenth of its
original volume, it must be diluted with ether. The reason for this is
that the next step is extraction of the ergot alkaloids into a tartaric-acid
solution, and it has been found that this is very difficult from pure
chloroform. When the solution is predominantly ether, the transfer of
the alkaloids into the tartaric-acid solution can be done efficiently. For
the drum-sized batch, add 30 gallons of ether and two gallons of
alcohol. Similarly, for smaller batches add three volumes of ether and a
At this point, an important matter must be addressed. This matter is
central snoopervision of chemical transactions. Note the "Love
Practical LSD Manufacture
Letters From The Heat" section at the end of this book concerning the
Chemical Diversion Trafficking Act of 1988, and its amendments
since then. This federal law requires chemical dealers to "identify
their customers, maintain retrievable records, and report suspicious
transactions" for a list of chemicals compiled a
ripped airomatic therapy synthetic cannaboind
Highs: Stimulant, mild hallucinogen, and also reputed to be an aphrodisiac by some users
the lysergic acid
suspension into solution.
Continue the stirring in the cold and dark for
half an hour, then add a previously-cooled solution of 21 grams
diethylamine in 100 ml dimethlyformamide.
Continue stirring in the
cold for half an hour, then allow the flask to warm to room
temperature while stirring for a couple of hours.
Next, the batch should be poured into a 1000 ml sep funnel, and
diluted with 400 ml chloroform. When a thorough mixing is achieved,
wash the chloroform with some 1-molar NaOH solution in water, and
then some plain water. The chloroform contains the product. It is next
evaporated off under a vacuum to yield an oily residue which is a
mixture of LSD and iso-LSD.
They are separated chromatographically
LSD From Lysergic Acid
as in the other methods, the iso-LSD converted to LSD as in the other
methods, then converted to tartrate salt as in the other methods.
9 Method X
About 1980, a major LSD-manufacturing operation was busted in
England in a police action called Operation Julie.
This name was
derived from the undercover agent who infiltrated the manufacture
group, and who spent a major part of her time milking the genitals of
those involved. At the trial, it was revealed that the chief cook of the
group had made a major advance in the field of LSD manufacture.
The nature of this innovation had remained a nagging mystery
throughout the writing of this book. Searching the Chem. Abstracts
for entries under LSD turned up nothing. After 1965, when acid
became illegal, the entries under LSD no longer included improved
cooking procedures. Rather, the section was filled with references to
studies showing that massive doses of LSD are bad for mice, and
forensic techniques for detecting LSD. This was clearly a waste of
A close reading of the listed chemicals in the "Love Letters From
the Heat" section at the end of this book provided the clues I needed to
solve the mystery.
Note that propionic anhydride is a listed
chemical under the Chemical Diversion Act, with a reporting
threshold of 1 gram. There is only one substance in the field of
Practical LSD Manufacture
clandestine drug manufacture where 1 gram is a significant amount —
Could it be that propionic anhydride forms a mixed anhydride with
lysergic acid? I returned to the Chem. Abstracts and searched under
lysergic acid and closely related compounds for references to the
formation of mixed anhydrides with propionic anhydride. I also looked
for listings under substances related to LSD referring to the use of
propionic anhydride in their manufacture.
On this I hit paydirt!
Beginning in the late 70s and continuing through the 80s there were
several references to the use of propionic anhydride to form mixed
anhydrides with substances closely related to lysergic acid, mostly the
9,10-dihydro derivative of lysergic acid where the double bond two
spaces upstream from the carboxyl group
LSD. The plating field is also
underserved because so many shops have been put out of business
due to tough environmental regulations. There are many people
looking for somebody to plate their old car or bike parts, and the oneman
plating shop is an old and respected tradition in the industry.
Metal plating uses all sorts of solvents, including all the ones
mentioned in this book, to clean and degrease the metal parts prior to
plating. Hydrazine is used to reduce hexavalent chrome in wastewater to
the trivalent state so that it may then be removed from the
wastewater by precipitation as the hydroxide. Hydrazine is also used in
electroless nickel baths which plate pure nickel, not the nickel
phosphorus alloy obtained from those baths which use hypophosphite as
the reducer. Hydrazine is also used in boilers to prevent oxygen
pitting. Chlorine and 12V4% bleach are used to destroy cyanide in the
wastewater. The lab of a plating shop can be stocked with items such as
2,4-pentanedione which is a transition metal chelator, and many
other items. I wouldn't try for diethylamine though.
The use of a false identity when founding a front operation adds a
layer of security for the operator. Loompanics has the most complete
selection of books covering this topic.
During the actual cooking process, I have emphasized the need to
keep making progress and not fiddle around. One must present as
small a target as possible by getting the stuff made, moved, and
operations shut down as rapidly as is compatible with the production of
quality acid. When you have made your million-dose score, don't go
back to the well for another try the next year. Take a vacation.
Due to the very small dosage size of acid, any reasonable lab-scale
production will produce at least tens of thousands of doses. Be
prepared to be able to move that much without having to meet
Keeping Out Of Trouble
"friends of friends." If all you want is some high-quality trips for
yourself and a close circle of friends, you are much better served with
TMA-2 made from calamus oil, or MDA made from sassafras oil.
I have long been an outspoken advocate of the need for a selfdestruct
device in a lab. One serves a great deal less time for acts of
mayhem than for drugs. An ideal self-destruct device is a stick of
dynamite already armed with fuse and cap, stored inside a metal can.
The can protects against small accidental fires leading to the big one.
If a squad of goons starts pounding down the doors, the selfdestruct
sequence is initiated by lighting the fuse, and then diving out
the window. The ensuing blast and solvent fire will erase all evidence of
drugs. Explaining why the blast coincided with the arrival of the
enemy is best left to your lying lawyer, but if you can't wreck your
own place, what has this country come to?
A bit of perimeter security is called for to slow up the
aforementioned goon squad, and allow sufficient time and warning so
that the s